Takhua Thung Police’s Lt Col Kittiphumi Na Thalang was alerted of the accident by the local Narainthon rescue centre at 1:50am.
Police arrived at the scene with rescue workers to find the damaged bus smashed into a tree.
The bus driver, Sarawuth Sooksawan, 38, from Wichit suffered two broken legs and was taken to Phang Nga Hospital along with five passengers who suffer injuries caused by the impact of the crash.
Two of the five passengers were severely injured suffering broken collarbones and hip injuries. The other three suffered only minor injuries police said.
Lt Col Kittiphumi said, “The bus was carrying 15 Thai people from Hatyai to Phuket. Passengers believe the driver fell asleep and this caused him to lose control of the vehicle and slam head on into the tree.
“We are waiting to question the driver and the injured passengers about the incident before conclude the investigation,” he said.