CCTV from Thepkrasattri Tambon Administrative Organisation (OrBorTor) showed the pickup travelling southbound on Thepkrasattri Rd at about 8am when it struck the Honda Wave motorbike, which in turn hit a power pole then spun across the road.
The pickup then ploughed into a series of roadside stalls at the market before being brought to a stop by a power pole.
One person injured was Bichuan Naebnian, an official from the Mueang Mai branch of the Kusoldharm Foundation. She was taken to Thalang Hospital.
The driver of the motorbike, Ms Suhaila Kasaw, appeared to have escaped without serious injuries.
Police reported those affected by the wipeout as five women: mobile phone stall operator Malina Santhong, fruit shop owner Nonglak Chuaykarn, dumpling shop operator Radjai Phlengngan, drink shop operator Rungpailin Boonyarit and noodle shop owner Mitchaya Srichampa.
Details of their injuries have yet to be made clear.
Police named the driver of the Bangkok-registered delivery pickup as Adikiat Phumrak. Rescue workers needed to cut him free from the wreck before rushing him to hospital.
The full extent of the property damage is currently being assessed, and officers are continuing their investigation, Thalang Police reported.