Pol Lt Thitiwat Asasingh of the Thalang Police was informed of the incident at 3:31pm.
Officers along with a medical team from Srisoonthorn Municipality rushed to the scene, a shophouse in Moo 5, Srisoonthorn, to find the man, Insorn Bousai, 56, in a state of intoxication.
His wife, Boonjun Buasai, 52, also from Chiang Mai, was bleeding profusely from a large wound to her right foot.
An axe was still lying on the floor inside the home.
Paramedics provided immediate first aid before rushing Ms Boonjun to Thalang Hospital.
Officers arrested Insorn at the home before taking him to Thalang Police Station for further questioning and further legal action, police confirmed