Patong Police were informed of the incident at 10:40pm.
The girl, Nbaa Bahnasi, from Jerusalem, was riding in the back of the tuk-tuk with her family when the accident happened on Thaweewong Rd (the beach road), Patong Police reported.
The tuk-tuk driver, Bunyang Kaewaksorn, 51, told police that he had to brake suddenly to avoid hitting a person crossing the road, which caused young Nbaa to fall from the back of tuk-tuk onto the road.
She was struck by a car travelling behind.
Nbaa was rushed to Patong Hospital, but pronounced dead from her injuries.
Patong Police are continuing their investigation into the accident.