The ministry will set up shops in areas where copycats are rampant and selling genuine products at prices similar to those of pirated goods.
Small retailers who want to switch to selling genuine products will be asked to join the programme.
Deputy Commerce Minister Natthawut Saikua said the programme will begin next month at Chatuchak Market, with plans to expand elsewhere.
The US Trade Representative (USTR) last year added eight “red zones” to its list of “notorious markets” under scrutiny in Thailand, including Chatuchak and several night markets.
Despite the Thai government declaring 2013 the Year of Intellectual Property Rights Protection, Thailand was included for a seventh straight year on the list of the world’s worst intellectual property violators in a USTR report released last month.
In theory a place on the list can bring punitive trade retaliation such as special duties and sanctions, but in practice this has never happened.
The USTR remains concerned, as it was last year, that Thailand has failed to pass laws protecting intellectual property, the agency said.
In related news, Mr Natthawut said officials investigated 1,977 piracy cases and seized 422,079 items in January and February. The number of piracy cases rose by 33.7 per cent and the number of items seized by 3 per cent.
In an attempt to raise awareness about the problem Mr Natthawut visited Phuket at the end of February, accompanied by former beauty queen Natalie Glebova, and helped in the destruction of 94,120 pirate items with a street value of B216 million.