Robert Xie is charged with killing his Chinese-born brother-in-law Norman Lin, Lin's wife Lily, her sister Irene, and two boys aged nine and 12 who cannot be named for legal reasons.
The family were found dead in their beds in July 2009 in a case that shocked the nation.
It was Xie and his wife Kathy Lin who discovered the bodies and called police, sparking a mammoth investigation spanning Australia and China.
Xie was eventually charged in May last year and in Sydney's Central Local Court Wednesday, Magistrate John Andrews decided there was a compelling enough case against him to take it to a jury trial.
Police allege Xie was motivated by greed and jealousy and stood to inherit the Lin family's news agency.
During committal proceedings, the defence argued the case was based almost entirely on speculation.