The US Embassy confirmed to The Phuket News that the American was missing, saying his full name was Brett Chapman Bean. He has short blonde hair, blue eyes, fair skin and is 6 feet 2 inches (188 cm) tall.
Police visited Mr Bean’s bungalow in Karon and found his passport, wallet, and other personal items.
They say a witness, named Danny, spoke with Mr Bean on November 25, but has not heard from him since then.
Anyone with information should contact the US Embassy in Bangkok on 02 2054049 or 02 -2054000 (24 hour number).